Scutellarein derivatives with histamine H3 receptor antagonism and cholinesterase inhibitory potency as multi target-directed ligands for possible Alzheimer’s disease therapy

Author:

Chen Jiao,He Zhu,Luo Keke,Luo Qianhen,Wang Yujie,Liu Ting,Li Li,Dai Zeqin,Yang Shenggang,Li Yongjun,Zhao Yonglong,Tang Lei,Fu Xiaozhong

Funder

Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents

National Aerospace Science Foundation of China

Key Program of NSFC-Tongyong Union Foundation

Guizhou Provincial Engineering Research Center for Natural Drugs, Guizhou Medical University

Publisher

Elsevier BV

Reference56 articles.

1. Alzheimer's disease facts and figures;Alzheimer’s Association;Alzheimer’s Dement.,2021

2. Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progression;Al-Onaizi;Brain Behav. Immun.,2022

3. P4–151: World Alzheimer report 2014: dementia and risk reduction;Wortmann;Alzheimer’s Dement.,2015

4. Therapeutics of Alzheimer’s disease: past, present and future;Anand;Neuropharmacology,2014

5. Alzheimer’s disease;Ballard;Lancet,2011

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