Design, synthesis, and antitumor activity evaluation of potent fourth-generation EGFR inhibitors for treatment of Osimertinib resistant non-small cell lung cancer (NSCLC)

Author:

Zhang Yuchen,Tong Lexian,Yan Fangjie,Huang Ping,Zhu Cheng-LiangORCID,Pan Chenghao

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference14 articles.

1. Cancer statistics 2023;Siegel;CA Cancer J. Clin.,2023

2. Lung cancer;Thai;Lancet,2021

3. Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy;Skoulidis;Nat. Rev. Cancer,2019

4. Recent advances of novel fourth generation EGFR inhibitors in overcoming C797S mutation of lung cancer therapy;Xu;Eur. J. Med. Chem.,2023

5. Tyrosine kinase inhibitors for the treatment of EGFR mutation-positive non-small-cell lung cancer: a clash of the generations;Shah;Clin. Lung Cancer,2020

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1. Phenotyping Tumor Heterogeneity through Proteogenomics: Study Models and Challenges;International Journal of Molecular Sciences;2024-08-14

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