Hydantoin based dual inhibitors of ALR2 and PARP-1: Design, synthesis, in-vitro and in-vivo evaluation-Reference-Cited by-同舟云学术

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Hydantoin based dual inhibitors of ALR2 and PARP-1: Design, synthesis, in-vitro and in-vivo evaluation

Published:2022-12 Issue: Volume:129 Page:106108
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Kumar Manoj,Kumar Singh Pankaj,Choudhary Shalki,Silakari Om

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Indian Council of Medical Research

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference26 articles.

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2. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas;Saeedi;Diabetes Res. Clin. Pract.,2019

3. Mechanisms of diabetic complications;Forbes;Physiol. Rev.,2013

4. The missing link: a single unifying mechanism for diabetic complications;Nishikawa;Kidney Int.,2000

5. Inhibition of glycation and aldose reductase activity using dietary flavonoids: A lens organ culture studies;Patil;Int. J. Biol. Macromol.,2017

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1. Selectivity challenges for aldose reductase inhibitors: A review on comparative SAR and interaction studies;Journal of Molecular Structure;2024-12

2. Synthesis of Tetracyclic Spirooxindolepyrrolidine-Engrafted Hydantoin Scaffolds: Crystallographic Analysis, Molecular Docking Studies and Evaluation of Their Antimicrobial, Anti-Inflammatory and Analgesic Activities;Molecules;2023-11-06

3. Design of a multi-target focused library for antidiabetic targets using a comprehensive set of chemical transformation rules;Frontiers in Pharmacology;2023-11-02

4. In vitro activity of novel 4-iminohydantoin sulfamide derivatives against human cytomegalovirus;Chemical Papers;2023-09-15

5. Novel O-benzylcinnamic acid derivative L26 treats acute lung injury in mice by MD-2;European Journal of Medicinal Chemistry;2023-04

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