Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy-Reference-Cited by-同舟云学术

Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy

Published:2023-02 Issue: Volume:131 Page:106282
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

González Myriam,Ellahioui Younes,Gallego Laura,Vicente-Blázquez Alba,Álvarez Raquel,Medarde Manuel,Peláez Rafael

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference46 articles.

1. Microtubule-binding agents: a dynamic field of cancer therapeutics;Dumontet;Nat. Rev. Drug Discov.,2010

2. Microtubules and resistance to tubulin-binding agents;Kavallaris;Nat. Rev. Cancer,2010

3. Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target;Vicente-Blazquez;Med. Res. Rev.,2019

4. Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain;Ravelli;Nature,2004

5. Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review;McLoughlin;Pharmaceuticals,2020

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