Generation of wild-type rat Glucocerebrosidase homology modeling: Identification of putative interactions site and mechanism for chaperone using combined in-silico and in-vitro studies-Reference-Cited by-同舟云学术

Generation of wild-type rat Glucocerebrosidase homology modeling: Identification of putative interactions site and mechanism for chaperone using combined in-silico and in-vitro studies

Published:2022-09 Issue: Volume:126 Page:105871
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Tripathi Pratigya,Ganeshpurkar Ankit,Singh Sushil Kumar,Krishnamurthy Sairam

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference34 articles.

1. Effects of ambroxol on the autophagy-lysosome pathway and mitochondria in primary cortical neurons;Magalhaes;Sci. Rep.,2018

2. Ambroxol modulates 6-Hydroxydopamine-induced temporal reduction in Glucocerebrosidase (GCase) enzymatic activity and Parkinson’s disease symptoms;Mishra;Biochem. Pharmacol.,2018

3. Ambroxol effects in glucocerebrosidase and α-synuclein transgenic mice;Migdalska-Richards;Ann. Neurol.,2016

4. Disease-modifying strategies for Parkinson's disease;Kalia;Mov. Disord.,2015

5. Ambroxol as a novel disease-modifying treatment for Parkinson’s disease dementia: protocol for a single-centre, randomized, double-blind, placebo-controlled trial;Silveira;BMC Neurol.,2019

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1. Identification of novel glucocerebrosidase chaperone for potential treatment of Parkinson's disease: An approach using in silico virtual screening, molecular docking and molecular dynamics, and in vitro studies;International Journal of Biological Macromolecules;2023-02