Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry
Reference35 articles.
1. What are the hallmarks of cancer?;Lazebnik;Nat. Rev. Cancer,2010
2. FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line;Sonoda;J. Biol. Chem.,1999
3. Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells;Hiscox;Breast Cancer Res. Treat.,2011
4. Focal adhesion kinase: a potential target in cancer therapy;van Nimwegen;Biochem. Pharmacol.,2007
5. Anti-apoptotic role of focal adhesion kinase (FAK);Sonoda;J. Biol. Chem.,2000
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. FAK inhibitors in cancer, a patent review – an update on progress;Expert Opinion on Therapeutic Patents;2024-07-02
2. N-Acylhydrazone Pharmacophore's Analgesic and Anti-inflammatory Profile: Recent Advancements during the Past Ten Years;Current Pharmaceutical Design;2024-02
3. Caspase-3 Activators as Anticancer Agents;Current Protein & Peptide Science;2023-12
4. Benzotriazole scaffold: An overview of antiproliferative potential, mechanisms of action, and structure–activity relationships;Archiv der Pharmazie;2023-06-06
5. Development of certain aminoquinazoline scaffolds as potential multitarget anticancer agents with apoptotic and anti-proliferative effects: Design, synthesis and biological evaluation;Bioorganic Chemistry;2023-06
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3