Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[( N -cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors-Reference-Cited by-同舟云学术

Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[( N -cycloalkylbenzamido)methyl]-2-quinolones as potential HIV-1 integrase inhibitors

Published:2017-12 Issue: Volume:75 Page:310-316
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Sekgota Khethobole C.,Majumder Swarup,Isaacs Michelle,Mnkandhla Dumisani,Hoppe Heinrich C.,Khanye Setshaba D.,Kriel Frederik H.,Coates Judy,Kaye Perry T.

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference25 articles.

1. Synthesis and in vitro anti-hepatitis B virus activities of 4-aryl-6-chloro-quinolin-2-one and 5-aryl-7-chloro-1,4-benzodiazepine derivatives

2. Synthesis of 5-Substituted-1H-indol-2-yl-1H-quinolin-2-ones: A Novel Class of KDR Kinase Inhibitors

3. Synthesis and biological evaluation of substituted 3-anilino-quinolin-2(1H)-ones as PDK1 inhibitors

4. Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility

5. Design of Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase with Improved Drug Resistance Properties. 2.

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