Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model-Reference-Cited by-同舟云学术

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Design, synthesis, evaluation and optimization of potent IRAK4 inhibitors alleviating production of inflammatory cytokines in LPS-induced SIRS model

Published:2023-08 Issue: Volume:137 Page:106584
ISSN:0045-2068
Container-title:Bioorganic Chemistry
language:en
Short-container-title:Bioorganic Chemistry

Author:

Hao Yongjin,Wang Jin,Ma Jiawan,Yu Xiaoliang,Li Zhanhui,Wu Shuwei,Tian Sheng,Ma Haikuo,He Sudan,Zhang Xiaohu

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Molecular Biology,Biochemistry

Reference51 articles.

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3. The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors;Kawai;Nat Immunol,2010

4. Recent progress in the molecular recognition and therapeutic importance of interleukin-1 receptor-associated kinase 4;Patra;Molecules,2016

5. The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling;Flannery;Biochem Pharmacol,2010

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