Unveiling the intra-tumor fate of trastuzumab deruxtecan in a xenograft model to support its mechanism of action-Reference-Cited by-同舟云学术

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Unveiling the intra-tumor fate of trastuzumab deruxtecan in a xenograft model to support its mechanism of action

Published:2024-06 Issue: Volume:56 Page:101001
ISSN:1347-4367
Container-title:Drug Metabolism and Pharmacokinetics
language:en
Short-container-title:Drug Metabolism and Pharmacokinetics

Author:

Nagai Yoko^ORCID,Oitate Masataka^ORCID,Shibayama Takahiro,Takakusa Hideo,Watanabe Nobuaki^ORCID

Publisher

Elsevier BV

Reference21 articles.

1. DS-8201a, a novel HER2-targeting ADC with a novel DNA topoisomerase I inhibitor, demonstrates a promising antitumor efficacy with differentiation from T-DM1;Ogitani;Clin Cancer Res,2016

2. The latest research and development into the antibody-drug conjugate, [fam-] trastuzumab deruxtecan (DS-8201a), for HER2 cancer therapy;Nakada;Chem Pharm Bull,2019

3. Trastuzumab deruxtecan in previously treated HER2-positive breast cancer;Modi;N Engl J Med,2020

4. Trastuzumab deruxtecan in previously treated HER2-positive gastric cancer;Shitara;N Engl J Med,2020

5. Trastuzumab deruxtecan versus trastuzumab emtansine for breast cancer;Cortés;N Engl J Med,2022

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