Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications-Reference-Cited by-同舟云学术

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Quantitative target engagement of RIPK1 in human whole blood via the cellular thermal shift assay for potential pre-clinical and clinical applications

Published:2023-12 Issue: Volume: Page:
ISSN:2472-5552
Container-title:SLAS Discovery
language:en
Short-container-title:SLAS Discovery

Author:

Patel Shitalben^ORCID,Karlsson Marie,Klahn Joseph T.,Gambino Frank,Costa Helena,McGuire Kathleen A.^ORCID,Baumgartner Christina K.^ORCID,Williams Jon,Sandoz Sarah,Kath James E.^ORCID

Publisher

Elsevier BV

Subject

Molecular Medicine,Biochemistry,Analytical Chemistry,Biotechnology

Reference32 articles.

1. A shift in thinking: cellular thermal shift assay-enabled drug discovery;Caballero;ACS Med Chem Lett,2023

2. The importance of PK–PD;Barrow;J Med Chem,2023

3. Role of receptor occupancy assays by flow cytometry in drug development;Stewart;Cytometry B Clin Cytom,2016

4. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay;Martinez Molina;Science,2013

5. A tale of two tails: efficient profiling of protein degraders by specific functional and target engagement readouts;Chernobrovkin;SLAS Discov,2021

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