Long-term abecarnil administration produces tolerance and withdrawal signs in the rat

Author:

Elliot Elizabeth E,White Jason M

Publisher

Elsevier BV

Subject

Pharmacology

Reference21 articles.

1. The first double-blind, placebo-controlled trial of a partial benzodiazepine agonist abecarnil (ZK 112-119) in generalized anxiety disorder;Ballenger;Psychopharmacol. Bull.,1991

2. Precipitated and spontaneous withdrawal following administration of lorazepam but not zolpidem;Elliot;Pharmacol. Biochem. Behav.,2000

3. Chronic treatment with diazepam or abecarnil affects the expression of GABAA receptor subunit mRNAs in the rat cortex;Holt;Neuropharmacology,1996

4. Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice;Jackson;Eur. J. Pharmacol.,1996

5. Pharmacokinetics of the anxiolytic β-carboline derivative abecarnil in the mouse, rat, rabbit, dog, cynomolgus monkey and baboon;Krause;Drug Res.,1990

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1. Anxioselective Compounds Acting at the GABAA Receptor Benzodiazepine Binding Site;Current Drug Target -CNS & Neurological Disorders;2003-08-01

2. Deficient prepulse inhibition of acoustic startle in Hooded-Wistar rats compared with Sprague-Dawley rats;Clinical and Experimental Pharmacology and Physiology;2003-04

3. Antianxiety Agents;Burger's Medicinal Chemistry and Drug Discovery;2003-01-15

4. Basic Pharmacologic Mechanisms Involved in Benzodiazepine Tolerance and Withdrawal;Current Pharmaceutical Design;2002-01-01

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