Denatured globular protein and bile salt-coated nanoparticles for poorly water-soluble drugs: Penetration across the intestinal epithelial barrier into the circulation system and enhanced oral bioavailability

Author:

He Wei,Yang Ke,Fan Lifang,Lv Yaqi,Jin Zhu,Zhu Shumin,Qin Chao,Wang Yiao,Yin Lifang

Funder

Natural Science Foundation of Jiangsu Province

Fostering Plan of University Scientific and Technological Innovation Team of Jiangsu Qing Lan Project

Fundamental Research Funds for the Central Universities

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference30 articles.

1. Freeze-drying of nanoparticles: formulation, process and storage considerations;Abdelwahed;Adv. Drug Deliv. Rev.,2006

2. Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt;Chen;Int. J. Pharm.,2009

3. Oral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers;Ensign;Adv. Drug Deliv. Rev.,2012

4. Nanoemulsion improves the oral absorption of candesartan cilexetil in rats: performance and mechanism;Gao;J. Control. Release,2011

5. Food protein-stabilized nanoemulsions as potential delivery systems for poorly water-soluble drugs: preparation, in vitro characterization, and pharmacokinetics in rats;He;Int. J. Nanomed.,2011

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