Lipid nanoparticles protect from edelfosine toxicity in vivo

Author:

Lasa-Saracíbar Beatriz,Aznar María Ángela,Lana Hugo,Aizpún Ismael,Gil Ana Gloria,Blanco-Prieto Maria J.

Funder

Caja Navarra Foundation

Spanish Ministry of Science and Innovation

Red Temática de Investigación Cooperativa en Cáncer

Fondo Europeo de Desarrollo Regional

Asociación de Amigos de la Universidad de Navarra

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference18 articles.

1. Effects of nanomaterial physicochemical properties on in vivo toxicity;Aillon;Adv. Drug Deliv. Rev.,2009

2. Lipid nanoparticles for brain targeting. III. Long-term stability and in vivo toxicity;Blasi;Int. J. Pharm.,2013

3. Comparative study of A HPLC–MS assay versus an UHPLC–MS/MS for anti-tumoral alkyl lysophospholipid edelfosine determination in both biological samples and in lipid nanoparticulate systems;Estella-Hermoso de Mendoza;J. Chromatogr. B,2009

4. Estella-Hermoso de Mendoza, A., Blanco-Prieto, M.J., Campanero, M.A., Mollinedo, F., Villa-Pulgarín, J., Varela, R., 2011. Development and use of lipidic nanoparticles loaded with edelfosine and ether phospholipids in antitumoral and antiparasitic therapy. Spanish Patent, P201130433, October 3.

5. In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma;Estella-Hermoso de Mendoza;J. Control. Release,2011

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