Practicality of non-invasive glucagon-loaded dissolving microneedle for life-saving treatment of severe hypoglycemia in a diabetic rat model

Author:

Wang Xuejiao,Ma Yinling,Qi Xiaodan,Ruan Xi,Cao Deying,Zhao FengORCID

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hebei Province

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference34 articles.

1. Streptozotocin-induced type 1 and 2 diabetes in rodents: a model for studying diabetic cardiac autonomic neuropath;Akinlade;Afr. Health Sci.,2021

2. Association DBOC., 2021. Guidelines for the prevention and treatment of type 2 diabetes mellitus in China (2020 Edition) (Part 2). Chin. J. Pract. Int. Med. 41, 757–874.

3. Structural refinement of glucagon for therapeutic use;Chabenne;J. Med. Chem.,2020

4. Panorama of dissolving microneedles for transdermal drug delivery;Dalvi;Life Sci.,2021

5. Preparation and characterization of fast dissolving ulvan microneedles for transdermal drug delivery system;Don;Int. J. Biol. Macromol.,2022

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