Gastrointestinal behavior of itraconazole in humans – Part 1: Supersaturation from a solid dispersion and a cyclodextrin-based solution-Reference-Cited by-同舟云学术

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Gastrointestinal behavior of itraconazole in humans – Part 1: Supersaturation from a solid dispersion and a cyclodextrin-based solution

Published:2017-06 Issue:1 Volume:525 Page:211-217
ISSN:0378-5173
Container-title:International Journal of Pharmaceutics
language:en
Short-container-title:International Journal of Pharmaceutics

Author:

Brouwers Joachim,Geboers Sophie,Mols Raf,Tack Jan,Augustijns Patrick

Funder

Innovative Medicines Initiative Joint Undertaking

European Union’s Seventh Framework Program

EFPIA

Research Foundation Flanders (FWO)

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference20 articles.

1. Population pharmacokinetic modeling of itraconazole and hydroxyitraconazole for oral suba-itraconazole and sporanox capsule formulations in healthy subjects in fed and fasted states;Abuhelwa;Antimicrob. Agents Chemother.,2015

2. Population in vitro-in vivo correlation model linking gastrointestinal transit time, pH, and pharmacokinetics: itraconazole as a model drug;Abuhelwa;Pharm. Res.,2016

3. Enhanced bioavailability of itraconazole in hydroxypropyl-beta-cyclodextrin solution versus capsules in healthy volunteers;Barone;Antimicrob. Agents Chemother.,1998

4. Drug supersaturation in simulated and human intestinal fluids representing different nutritional states;Bevernage;J. Pharm. Sci.,2010

5. Supersaturation in human gastric fluids;Bevernage;Eur. J. Pharm. Biopharm.,2012

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1. On the processes limiting oral drug absorption when amorphous solid dispersions are administered after a high-calorie, high-fat meal: Sporanox® pellets;European Journal of Pharmaceutical Sciences;2024-08

2. The Dynamic Intestinal Absorption Model (Diamod®), an in vitro tool to study the interconnected kinetics of gastrointestinal solubility, supersaturation, precipitation, and intestinal permeation processes of oral drugs;International Journal of Pharmaceutics: X;2023-12

3. Levocetirizine-Loaded Electrospun Fibers from Water-Soluble Polymers: Encapsulation and Drug Release;Molecules;2023-05-19

4. When Interactions Between Bile Salts and Cyclodextrin Cause a Negative Food Effect: Dynamic Dissolution/Permeation Studies with Itraconazole (Sporanox®) and Biomimetic Media;Journal of Pharmaceutical Sciences;2023-05

5. Application of tiny-TIM as a mechanistic tool to investigate the in vitro performance of different itraconazole formulations under physiologically relevant conditions;European Journal of Pharmaceutical Sciences;2022-06

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