Effects of the phosphodiesterase 4 inhibitors SB 207499 and AWD 12-281 on the inflammatory reaction in a model of allergic dermatitis

Author:

Bäumer Wolfgang,Gorr Gilbert,Hoppmann Joachim,Ehinger Andreas M,Ehinger Britt,Kietzmann Manfred

Publisher

Elsevier BV

Subject

Pharmacology

Reference30 articles.

1. Increased leukocyte histamine release with elevated cyclic AMP-phosphodiesterase activity in atopic dermatitis;Butler;J. Allergy Clin. Immunol.,1983

2. Cyclic nucleotide phosphodiesterase 4 subtypes are differentially expressed by primary keratinocytes and human epidermoid cell lines;Chujor;J. Invest. Dermatol.,1998

3. Phosphodiesterase inhibition by Ro 20-1724 reduces hyper-IgE synthesis by atopic dermatitis cells in vitro;Cooper;J. Invest. Dermatol.,1985

4. Murine mast cells exposed to mercuric chloride release granule-associated N-acetyl-beta-d-hexosaminidase and secrete interleukin 4 and TNF-alpha;Dastych;J. Allergy Clin. Immunol.,1999

5. Suppression of human eosinophil respiratory burst and cyclic AMP hydrolysis by inhibitors of type IV phosphodiesterase: interaction with the beta adrenoreceptor agonist albuterol;Dent;J. Pharmacol. Exp. Ther.,1994

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