International prevalidation studies of the EpiDerm™ 3D human reconstructed skin micronucleus (RSMN) assay: Transferability and reproducibility

Author:

Aardema Marilyn J.,Barnett Brenda C.,Khambatta Zubin,Reisinger Kerstin,Ouedraogo-Arras Gladys,Faquet Brigitte,Ginestet Anne-Claire,Mun Greg C.,Dahl Erica L.,Hewitt Nicola J.,Corvi Raffallea,Curren Rodger D.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference21 articles.

1. EU, 2003, EC-Directive 2003/15/EC of the European Parliament and of the Council of 27 February 2003 amending Council Directive 76/768/EEC on the approximation of the laws of the Member States relating to cosmetic products, Official Journal L66, 11/03/2003, p. 26.

2. REACh, http://ec.europa.eu/environment/chemicals/reach/reach_intro.htm.

3. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity;Kirkland;Mutat. Res.,2005

4. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. II. Further analysis of mammalian cell results, relative predictivity and tumour profiles;Kirkland;Mutat. Res.,2006

5. Development of a method for assessing micronucleus induction in a 3D human skin model EpiDerm™;Curren;Mutat. Res.,2006

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