Exome Sequencing Implicates an Increased Burden of Rare Potassium Channel Variants in the Risk of Drug-Induced Long QT Interval Syndrome-Reference-Cited by-同舟云学术

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Exome Sequencing Implicates an Increased Burden of Rare Potassium Channel Variants in the Risk of Drug-Induced Long QT Interval Syndrome

Published:2014-04 Issue:14 Volume:63 Page:1430-1437
ISSN:0735-1097
Container-title:Journal of the American College of Cardiology
language:en
Short-container-title:Journal of the American College of Cardiology

Author:

Weeke Peter,Mosley Jonathan D.,Hanna David,Delaney Jessica T.,Shaffer Christian,Wells Quinn S.,Van Driest Sara,Karnes Jason H.,Ingram Christie,Guo Yan,Shyr Yu,Norris Kris,Kannankeril Prince J.,Ramirez Andrea H.,Smith Joshua D.,Mardis Elaine R.,Nickerson Deborah,George Alfred L.,Roden Dan M.

Funder

Fondation Leducq

Vanderbilt Ingram Cancer Center

Vanderbilt Vision Center

NIH/NCRR

Clinical Pharmacology

Tryg Foundation

Gilead Sciences

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference37 articles.

1. Molecular and cellular mechanisms of cardiac arrhythmias;Keating;Cell,2001

2. Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview;De Ponti;Drug Saf,2002

3. Drug-induced prolongation of the QT interval;Roden;N Engl J Med,2004

4. Genetic susceptibility to acquired long QT syndrome: pharmacologic challenge in first-degree relatives;Kannankeril;Heart Rhythm,2005

5. HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin;Daly;Nat Genet,2009

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1. The electrophysiologic effects of KCNQ1 extend beyond expression of IKs: evidence from genetic and pharmacologic block;Cardiovascular Research;2024-03-05

2. Genetic risk factors for drug-induced long QT syndrome: findings from a large real-world case–control study;Pharmacogenomics;2024-02

3. Genetic factors contribute to medication-induced QT prolongation: A review;Psychiatry Research;2022-11

4. The genetics of drug-induced QT prolongation: evaluating the evidence for pharmacodynamic variants;Pharmacogenomics;2022-06

5. Rare Variation in Drug Metabolism and Long QT Genes and the Genetic Susceptibility to Acquired Long QT Syndrome;Circulation: Genomic and Precision Medicine;2022-02

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