Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G-Reference-Cited by-同舟云学术

Chromatin-mediated depression of fractionation performance on electronegative multimodal chromatography media, its prevention, and ramifications for purification of immunoglobulin G

Published:2014-12 Issue: Volume:1374 Page:145-155
ISSN:0021-9673
Container-title:Journal of Chromatography A
language:en
Short-container-title:Journal of Chromatography A

Author:

Gagnon Pete,Nian Rui,Tan Lihan,Cheong Jason,Yeo Veronica,Yang Yuansheng,Gan Hui Theng

Funder

Exploit Technologies Pte. Ltd.

Validated Biosystems

Biomedical Research Council of the Singapore Agency for Science and Technology Research

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference55 articles.

1. An exclusion mechanism in ion exchange chromatography;Harinarayan;Biotechnol. Bioeng.,2006

2. Advances in technology and process development for industrial-scale monoclonal antibody purification;Fontes,2009

3. Host cell protein clearance during protein A chromatography: development of an improved column wash step;Shukla;Biotechnol. Prog.,2008

4. Characterization and removal of aggregates formed by nonspecific interaction of IgM monoclonal antibodies with chromatin catabolites during cell culture production;Gan;J. Chromatogr. A,2013

5. Chromatographic behavior of IgM:DNA complexes;Gagnon;J. Chromatogr. A,2011

Cited by 33 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Host cell protein networks as a novel co‐elution mechanism during protein A chromatography;Biotechnology and Bioengineering;2024-03-07

2. Factors affecting product association as a mechanism of host‐cell protein persistence in bioprocessing;Biotechnology and Bioengineering;2024-01-19

3. Biomimetic affinity chromatography for antibody purification: Host cell protein binding and impurity removal;Journal of Chromatography A;2023-09

4. Behavior of host-cell-protein-rich aggregates in antibody capture and polishing chromatography;Journal of Chromatography A;2023-08

5. Analytical characterization of host‐cell‐protein‐rich aggregates in monoclonal antibody solutions;Biotechnology Progress;2023-04-05