Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins
Author:
Funder
Université de Genève
Universitat de València
Publisher
Elsevier BV
Subject
Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry
Reference37 articles.
1. Ion-exchange chromatography for the characterization of biopharmaceuticals;Fekete;J. Pharm. Biomed. Anal.,2015
2. Modeling of salt and pH gradient elution inion-exchange chromatography;Schmidt;J. Sep. Sci.,2014
3. Improving pH gradient cation-exchange chromatography of monoclonal antibodies by controlling ionic strength;Zhang;J. Chromatogr. A,2013
4. Rapid charge variant analysis of monoclonal antibodies to support lead candidate biopharmaceutical development;Trappe;J. Chromatogr. B,2018
5. Investigation of degradation processes in IgG1 monoclonal antibodies by limited proteolysis coupled with weak cation-exchange HPLC;Lau;J. Chromatogr. B,2010
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