High-throughput multiplex analysis of mAb aggregates and charge variants by automated two-dimensional size exclusion-cation exchange chromatography coupled to mass spectrometry-Reference-Cited by-同舟云学术

High-throughput multiplex analysis of mAb aggregates and charge variants by automated two-dimensional size exclusion-cation exchange chromatography coupled to mass spectrometry

Published:2022-05 Issue: Volume:1670 Page:462944
ISSN:0021-9673
Container-title:Journal of Chromatography A
language:en
Short-container-title:Journal of Chromatography A

Author:

Lambiase Giulia^ORCID,Inman Sophie E.,Muroni Maurizio,Lindo Vivian^ORCID,Dickman Mark J.,James David C.

Funder

AstraZeneca PLC

University of Sheffield

Publisher

Elsevier BV

Subject

Organic Chemistry,General Medicine,Biochemistry,Analytical Chemistry

Reference22 articles.

1. Characterization of therapeutic antibodies and related products;Beck;Anal. Chem.,2012

2. Chemical and physical instabilities in manufacturing and storage of therapeutic proteins;Krause;Curr. Opin. Biotechnol.,2019

3. From cell line development to the formulated drug product: the art of manufacturing therapeutic monoclonal antibodies;Carrara;Int. J. Pharm.,2021

4. Developability assessment for monoclonal antibody drug candidates;Garripelli;Pharm. Dev. Technol.,2020

5. Physicochemical characterization of biopharmaceuticals;Parr;J. Pharm. Biomed. Anal.,2016

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