Preparation and in vitro biological evaluation of the enantiomers of the diydropyridine BMY 20014, a combination calcium and α1-adrenoreceptor antagonist-Reference-Cited by-同舟云学术

Preparation and in vitro biological evaluation of the enantiomers of the diydropyridine BMY 20014, a combination calcium and α1-adrenoreceptor antagonist

Published:1993-04 Issue:4 Volume:3 Page:561-564
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Lawson John E.,Poindexter Graham S.,Owens Donald A.,Cavanagh Robert L.,Goggins Gregory D.,Sarmiento J.George,Bleiberg Bonnie B.,Weselcouch Edward O.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference20 articles.

1. New insights and new approaches for the treatment of essential hypertension: Selection of therapy based on coronary heart disease risk factor analysis, hemodynamic profiles, quality of life, and subsets of hypertension

2. Calcium channel blockers. Potential medical benefits and side effects.

3. alpha 1-antagonists in the treatment of hypertension.

4. Selective alpha1-adrenergic blockade, lipids, and coronary heart disease risk

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3. Cardiovascular hybrid drugs: combination of more than one pharmacological property in one single molecule;European Journal of Pharmaceutical Sciences;1996-01

4. Metalation of Hantzsch esters and mixed amide esters: a general route to C-2 functionalized 1,4-dihydropyridines;The Journal of Organic Chemistry;1993-07