Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase η and reduces DNA synthesis fidelity
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology,Biochemistry
Reference88 articles.
1. How DNA polymerases catalyse replication and repair with contrasting fidelity;Wu;Nat. Rev. Chem.,2017
2. Translesion and repair DNA polymerases: diverse structure and mechanism;Yang;Annu. Rev. Biochem.,2018
3. Watching DNA polymerase η make a phosphodiester bond;Nakamura;Nature,2012
4. Capture of a third Mg2+ is essential for catalyzing DNA synthesis;Gao;Science,2016
5. In crystallo observation of three metal ion promoted DNA polymerase misincorporation;Chang;Nat. Commun.,2022
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Sugar ring alignment and dynamics underline cytarabine and gemcitabine inhibition on Pol η catalyzed DNA synthesis;Journal of Biological Chemistry;2024-06
2. In crystallo observation of active site dynamics and transient metal ion binding within DNA polymerases;Structural Dynamics;2023-05-01
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