Aqueous two-phase extraction as a platform in the biomanufacturing industry: Economical and environmental sustainability

Author:

Rosa P.A.J.,Azevedo A.M.,Sommerfeld S.,Bäcker W.,Aires-Barros M.R.

Funder

Sixth Research Framework Programme of the European Union

Fundação para a Ciência e Tecnologia

Portuguese Ministry for Science, Technology and Higher Education

Publisher

Elsevier BV

Subject

Biotechnology,Bioengineering,Applied Microbiology and Biotechnology

Reference38 articles.

1. Partition of Cell Particles and Macromolecules;Albertsson,1986

2. Partitioning and purification of monoclonal antibodies in aqueous two-phase systems;Andrews;Bioseparation,1996

3. Integrated process for the purification of antibodies combining aqueous two-phase extraction, hydrophobic interaction chromatography and size-exclusion chromatography;Azevedo;J Chromatogr A,2008

4. Downstream processing of human antibodies integrating an extraction capture step and cation exchange chromatography;Azevedo;J Chromatogr B,2009

5. Chromatography-free recovery of biopharmaceuticals through aqueous two-phase processing;Azevedo;Trends Biotechnol,2009

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