Improved Prediction of the Drug-Drug Interactions of Pemafibrate Caused by Cyclosporine A and Rifampicin via PBPK Modeling: Consideration of the Albumin-Mediated Hepatic Uptake of Pemafibrate and Inhibition Constants With Preincubation Against OATP1B-Reference-Cited by-同舟云学术

Improved Prediction of the Drug-Drug Interactions of Pemafibrate Caused by Cyclosporine A and Rifampicin via PBPK Modeling: Consideration of the Albumin-Mediated Hepatic Uptake of Pemafibrate and Inhibition Constants With Preincubation Against OATP1B

Published:2021-01 Issue:1 Volume:110 Page:517-528
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Park Ji Eun,Shitara Yoshihisa,Lee Wooin,Morita Shigemichi,Sahi Jasminder,Toshimoto Kota,Sugiyama Yuichi

Publisher

Elsevier BV

Subject

Pharmaceutical Science

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3. Efficacy and safety of pemafibrate (K-877), a selective peroxisome proliferator-activated receptor alpha modulator, in patients with dyslipidemia: results from a 24-week, randomized, double blind, active-controlled, phase 3 trial;Ishibashi;J Clin Lipidol,2018

4. Rationale and design of the pemafibrate to reduce cardiovascular outcomes by reducing triglycerides in patients with diabetes (PROMINENT) study;Pradhan;Am Heart J,2018

5. Plasma concentrations of pemafibrate with co-administered drugs predicted by physiologically based pharmacokinetic modeling in virtual populations with renal/hepatic impairment;Ogawa;Xenobiotica,2020

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1. Pemafibrate;Clinical Lipidology;2024

2. Unlocking the Potential of Drug Delivery Systems: A Comprehensive Review of Formulation Strategies and Technologies in the Field of Pharmaceutics;Current Drug Therapy;2023-11-22

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