A Radioactivity-mass Spectrometry Calibration Method Coupled with Biosynthesis to Generate a Metabolite Standard for Enzyme Kinetics Studies-Reference-Cited by-同舟云学术

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A Radioactivity-mass Spectrometry Calibration Method Coupled with Biosynthesis to Generate a Metabolite Standard for Enzyme Kinetics Studies

Published:2024-09 Issue:9 Volume:113 Page:2933-2939
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Wang Ting^ORCID,Thomas Cody^ORCID,Latli Bachir^ORCID,Hrapchak Matt,Taub Mitchell E.

Publisher

Elsevier BV

Reference17 articles.

1. A rapid method for quantitatively estimating metabolites in human plasma in the absence of synthetic standards using a combination of liquid chromatography/mass spectrometry and radiometric detection;ChungPing;Rapid Commun Mass Spectromet,2007

2. Metabolism of imipramine in vitro by isozyme CYP2D6 expressed in a human cell line, and observations on metabolite stability;Coutts;J Chromatogr B: Biomed Sci Appl,1993

3. Metabolism of 14C-Imipramine;Crammer;Psychopharmacologia,1968

4. Drug metabolism in preclinical drug development: a survey of the discovery process, toxicology, and computational tools;Issa;Curr Drug Metab,2017

5. Substrate depletion approach for determining in vitro metabolic clearance: time dependencies in hepatocyte and microsomal incubations;Jones;Drug Metab Dispos,2004

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