Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture-Reference-Cited by-同舟云学术

Physiologically Based Pharmacokinetic Modeling of 3 HIV Drugs in Combination and the Role of Lymphatic System after Subcutaneous Dosing. Part 1: Model for the Free-Drug Mixture

Published:2022-02 Issue:2 Volume:111 Page:529-541
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Perazzolo Simone^ORCID,Shireman Laura M.^ORCID,Shen Danny D.^ORCID,Ho Rodney J.Y.

Funder

National Institutes of Health

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference52 articles.

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3. The role of secondary lymphatic tissue in immune deficiency of HIV infection;Schacker;AIDS,2008

4. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease;Pantaleo;Nature,1993

5. Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma;Kraft;AIDS,2017

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