AKT1 induces caspase-mediated cleavage of the CDK inhibitor p27Kip1 during cell cycle progression in leukemia cells transformed by FLT3-ITD
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Oncology,Hematology
Reference39 articles.
1. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
2. Analysis of FLT3-activating mutations in 979 patients with acute myelogeneous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis;Thiede;Blood,2002
3. Constitutive activation of Akt by Flt3 internal tandem duplications is necessary for increased survival, proliferation, and myeloid transformation;Brandts;Cancer Res,2005
4. FLT3 ligand regulates apoptosis through AKT-dependent inactivation of transcription factor FoxO3;Jonsson;Biochem Biophys Res Commun,2004
5. Constitutive phosphorylation of Akt/PKB protein in acute myeloid leukemia: its significance as a prognostic variable;Min;Leukemia,2003
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