AML with gain of chromosome 8 as the sole chromosomal abnormality (+8sole) is associated with a specific molecular mutation pattern including ASXL1 mutations in 46.8% of the patients-Reference-Cited by-同舟云学术

AML with gain of chromosome 8 as the sole chromosomal abnormality (+8sole) is associated with a specific molecular mutation pattern including ASXL1 mutations in 46.8% of the patients

Published:2015-03 Issue:3 Volume:39 Page:265-272
ISSN:0145-2126
Container-title:Leukemia Research
language:en
Short-container-title:Leukemia Research

Author:

Alpermann Tamara,Haferlach Claudia,Eder Christiane,Nadarajah Niroshan,Meggendorfer Manja,Kern Wolfgang,Haferlach Torsten,Schnittger Susanne

Publisher

Elsevier BV

Subject

Cancer Research,Oncology,Hematology

Reference39 articles.

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2. Primary vs. secondary neoplasia-associated chromosomal abnormalities – balanced rearrangements vs. genomic imbalances?;Johansson;Genes Chromosome Cancer,1996

3. +8 or trisomy 8. Atlas of genetics and cytogenetics in oncology and haematology;Huret,2007

4. Trisomy 8 in myelodysplasia and acute leukemia is constitutional in 15–20% of cases;Maserati;Genes Chromosome Cancer,2002

5. The incidence of trisomy 8 as a sole chromosomal aberration in myeloid malignancies varies in relation to gender, age, prior iatrogenic genotoxic exposure, and morphology;Paulsson;Cancer Genet Cytogenet,2001

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