Prevention of LLC-PK1 cell overgrowth in a bioartificial renal tubule device using a MEK inhibitor, U0126

Author:

Inagaki Miho,Yokoyama Tun A.,Sawada Kaichiro,Duc Vu M.,Kanai Genta,Lu Jianxin,Kakuta Takatoshi,Saito Akira

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference31 articles.

1. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture;Cory;Cancer Commun.,1991

2. MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?;Fanger;Curr. Opin. Genet. Dev.,1997

3. Identification of a novel inhibitor of mitogen-activated protein kinase kinase;Favata;J. Biol. Chem.,1998

4. Evaluation of Na+ active transport and morphological changes for bioartificial renal tubule cell device using Madin–Darby canine kidney cells;Fujita;Tissue Eng.,2002

5. U0126 reverses Ki-ras-mediated transformation by blocking both mitogen-activated protein kinase and p70 S6 kinase pathways;Fukazawa;Cancer Res.,2000

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