Efficient cascade synthesis of ampicillin from penicillin G potassium salt using wild and mutant penicillin G acylase from Alcaligenes faecalis
Author:
Publisher
Elsevier BV
Subject
Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering
Reference37 articles.
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2. The role of hydrophobic active-site residues in substrate specificity and acyltransfer activity of penicillin acylase;Alkema;Eur. J. Biochem.,2002
3. The sequence and crystal structure of the α-amino acid ester hydrolase from Xanthomonas citri define a new family of β-lactam antibiotic acylases;Barends;J. Biol. Chem.,2003
4. Penicillin G acylase from Achromobacter sp. CCM 4824: an efficient biocatalyst for syntheses of beta-lactam antibiotics under conditions employed in large-scale processes;Bečka;Appl. Microbiol. Biotechnol.,2014
5. Synthesis of β-lactam antibiotics containing α-aminophenylacetyl group in the acyl moiety catalyzed by d-(−)-phenylglycyl-β-lactamide amidohydrolase;Blinkovsky;Enzyme Microb. Technol.,1993
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