Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases-Reference-Cited by-同舟云学术

Decreasing lactate level and increasing antibody production in Chinese Hamster Ovary cells (CHO) by reducing the expression of lactate dehydrogenase and pyruvate dehydrogenase kinases

Published:2011-04 Issue:1-2 Volume:153 Page:27-34
ISSN:0168-1656
Container-title:Journal of Biotechnology
language:en
Short-container-title:Journal of Biotechnology

Author:

Zhou Meixia,Crawford Yongping,Ng Domingos,Tung Jack,Pynn Abigail F.J.,Meier Angela,Yuk Inn H.,Vijayasankaran Natarajan,Leach Kimberly,Joly John,Snedecor Bradley,Shen Amy

Publisher

Elsevier BV

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology,Bioengineering

Reference23 articles.

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3. Engineering of a mammalian cell line for reduction of lactate formation and high monoclonal antibody production;Chen;Biotechnol. Bioeng.,2001

4. Effects of ammonia and lactate on growth, metabolism, and productivity of BHK cells;Cruz;Enzyme Microb. Technol.,2000

5. Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes;Dietl;J. Immunol.,2010

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