A conserved role for AKT in the replication of emerging flaviviruses in vertebrates and vectors

Author:

Palmero Casanova Blanca,Albentosa González Laura,Maringer Kevin,Sabariegos Rosario,Mas AntonioORCID

Funder

Pirbright Institute

Universidad de Castilla-La Mancha

Agencia Estatal de Investigación

Biotechnology and Biological Sciences Research Council

Junta de Comunidades de Castilla-La Mancha

National Institutes of Health

Publisher

Elsevier BV

Reference83 articles.

1. Discovery of 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide (AZD5363), an orally bioavailable, potent inhibitor of Akt kinases;Addie;J. Med. Chem.,2013

2. Usutu virus: an emerging flavivirus with potential threat to public health in Africa: nigeria as a case study;Akinsulie;Front. Vet. Sci.,2023

3. Akt Kinase Intervenes in Flavivirus Replication by Interacting with Viral Protein NS5;Albentosa-Gonzalez;Viruses.,2021

4. Akt Interacts with Usutu Virus Polymerase, and Its Activity Modulates Viral Replication;Albentosa-Gonzalez;Pathogens.,2021

5. Molecular insights into the behavior of the allosteric and ATP-competitive inhibitors in interaction with AKT1 protein: a molecular dynamics study;Amiran;Int. J. Biol. Macromol.,2023

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