Lack of mammalian mutagenicity of the potent bacterial mutagen tris(2,3-dibromopropyl)phosphate and its metabolite 2-bromoacrolein

Author:

van Beerendonk Geertje J.M,Klein Johanna C,Tijdens Roeline B,Lichtenauer-Kaligis Elgin G.R,Tasseron-de Jong Judith G,Meerman John H.N

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference38 articles.

1. Biological interactions of α,β unsaturated aldehydes;Witz;Free Rad. Biol. Med.,1989

2. Activation mechanism of tris(2,3-dibromopropyl)phosphate to the potent mutagen 2-bromoacrolein;Nelson;Biochem. Biophys. Res. Commun.,1984

3. Mutagenic activation of tris(2,3-dibromopropyl)phosphate: the role of microsomal metabolism;Søderlund;Acta Pharmacol. Toxicol.,1979

4. Detection and mechanism of formation of the direct acting mutagen 2-bromoacrolein from 1,2-dibromo-3-chloropropane;Omichinski;Toxicol. Appl. Pharmacol.,1988

5. Genotoxicity of the flame retardant tris(2,3-dibromopropyl)phosphate in the rat and Drosophila: effects of deuterium substitution;Van Beerendonk;Carcinogenesis,1994

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