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Mitochondrial Lon protease controls ROS-dependent apoptosis in cardiomyocyte under hypoxia

  • Published:2015-07 Issue: Volume:23 Page:7-16
  • ISSN:1567-7249
  • Container-title:Mitochondrion
  • language:en
  • Short-container-title:Mitochondrion

Author:

Kuo Chan-Yen,Chiu Yi-Chieh,Lee Alan Yueh-Luen,Hwang Tsong-Long

Funder

Ministry of Science and Technology

Chang Gung Memorial Hospital

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Molecular Medicine

Reference36 articles.

1. Autophagy: dual roles in life and death? Nature reviews;Baehrecke;Mol. Cell. Biol.,2005

2. The cardiac mitochondrion: nexus of stress;Baines;Annu. Rev. Physiol.,2010

3. Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism;Bota;Nat. Cell Biol.,2002

4. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death;Bota;Free Radic. Biol. Med.,2005

5. Redox signaling in cardiac physiology and pathology;Burgoyne;Circ. Res.,2012
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