In vitro–in vivo extrapolation of drug-induced proarrhythmia predictions at the population level-Reference-Cited by-同舟云学术

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In vitro–in vivo extrapolation of drug-induced proarrhythmia predictions at the population level

Published:2014-03 Issue:3 Volume:19 Page:275-281
ISSN:1359-6446
Container-title:Drug Discovery Today
language:en
Short-container-title:Drug Discovery Today

Author:

Polak Sebastian,Wiśniowska Barbara,Fijorek Kamil,Glinka Anna,Mendyk Aleksander

Funder

Polish National Center for Research and Development

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology

Reference66 articles.

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2. Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes;Davies;PLoS One,2009

3. Torsade de pointes induced by systemic antifungal agents: lessons from a retrospective analysis of published case reports;Justo;Mycoses,2006

4. Trends in risks associated with new drug development: success rates for investigational drugs;DiMasi;Clin. Pharmacol. Ther.,2010

5. Impact and frequency of different toxicities throughout the pharmaceutical life cycle;Redfern;Toxicologist,2010

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3. Testing the limits of cardiac electrophysiology models through systematic variation of current;AIMS Mathematics;2020

4. Virtual Thorough QT (TQT) Trial—Extrapolation of In Vitro Cardiac Safety Data to In Vivo Situation Using Multi-Scale Physiologically Based Ventricular Cell-wall Model Exemplified with Tolterodine and Fesoterodine;The AAPS Journal;2018-07-11

5. Physiologically based pharmacokinetic-quantitative systems toxicology and safety (PBPK-QSTS) modeling approach applied to predict the variability of amitriptyline pharmacokinetics and cardiac safety in populations and in individuals;Journal of Pharmacokinetics and Pharmacodynamics;2018-06-25

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