In vivo evaluation of [18F]FEAnGA-Me: a PET tracer for imaging β-glucuronidase (β-GUS) activity in a tumor/inflammation rodent model

Author:

Antunes Inês F.,Haisma Hidde J.,Elsinga Philip H.,Sijbesma Jurgen W.A.,Waarde Aren van,Willemsen Antoon T.M.,Dierckx Rudi A.,de Vries Erik F.J.

Publisher

Elsevier BV

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference15 articles.

1. Synthesis and evaluation of [18F]-FEAnGA as a PET Tracer for beta-glucuronidase activity;Antunes;Bioconjugate Chem,2010

2. Antunes IF, Haisma HJ, Elsinga PH, van Waarde A, Willemsen ATM, Dierckx RA, de Vries EFJ. In vivo evaluation of 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-b-d-glucopyronuronate: a positron emission tomographic tracer for imaging b-glucuronidase activity in a tumor/inflammation rodent model. Molecular Imaging 2011 [in press].

3. Distribution and pharmacokinetics of the prodrug daunorubicin-GA3 in nude mice bearing human ovarian cancer xenografts;Houba;Biochem Pharmacol,1999

4. A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer;Houba;Br J Cancer,2001

5. A methylester of the glucuronide prodrug DOX-GA3 for improvement of tumor-selective chemotherapy;de Graaf;Biochem Pharmacol,2004

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