Radiation enhancement by the combined use of topoisomerase I inhibitors, RFS-2000 or CPT-11, and topoisomerase II inhibitor etoposide in human lung cancer cells

Author:

Kim Jae-Sung,Amorino George P.,Pyo Hongryull,Cao Qianwen,Choy Hak

Publisher

Elsevier BV

Subject

Radiology Nuclear Medicine and imaging,Oncology,Hematology

Reference38 articles.

1. Preclinical evaluation of the orally active camptothecin analog, RFS-2000 (9-nitro-20(S)-camptothecin) as a radiation enhancer;Amorino;Int J Radiat Oncol Biol Phys,2000

2. Inhibition of potentially lethal DNA damage repair in human tumor cells by beta-lapachone, an activator of topoisomerase I;Boothman;Cancer Res,1989

3. Posttreatment exposure to camptothecin enhances the lethal effects of X-rays on radioresistant human malignant melanoma cells;Boothman;Int J Radiat Oncol Biol Phys,1992

4. Mechanistic aspects of type-I topoisomerases;Champoux,1990

5. Mammalian DNA topoisomerase I mediates the enhancement of radiation cytotoxicity by camptothecin derivatives;Chen;Cancer Res,1997

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