Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent-Reference-Cited by-同舟云学术

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent

Published:2017-10 Issue:1 Volume:21 Page:17-26
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Gomes-Silva Diogo,Mukherjee Malini,Srinivasan Madhuwanti,Krenciute Giedre,Dakhova Olga,Zheng Yueting,Cabral Joaquim M.S.,Rooney Cliona M.,Orange Jordan S.,Brenner Malcolm K.,Mamonkin Maksim

Funder

NIH

ASH Scholar Award

Fundação para a Ciência e Tecnologia

Cancer Center

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference34 articles.

1. Fas ligand mediates activation-induced cell death in human T lymphocytes;Alderson;J. Exp. Med.,1995

2. Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression;Baetu;J. Immunol.,2001

3. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia;Brentjens;Sci. Transl. Med.,2013

4. Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment;Chan;Mol. Cell. Biol.,1999

5. COSMID: A web-based tool for identifying and validating CRISPR/Cas off-target sites;Cradick;Mol. Ther. Nucleic Acids,2014

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