Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay-Reference-Cited by-同舟云学术

Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay

Published:2024-04 Issue:4 Volume:43 Page:114098
ISSN:2211-1247
Container-title:Cell Reports
language:en
Short-container-title:Cell Reports

Author:

Bicknell Alicia A.^ORCID,Reid David W.^ORCID,Licata Marissa C.,Jones Adriana K.,Cheng Yi Min,Li Mengying,Hsiao Chiaowen Joyce,Pepin Christopher S.,Metkar Mihir,Levdansky Yevgen,Fritz Brian R.,Andrianova Elizaveta A.,Jain Ruchi,Valkov Eugene,Köhrer Caroline,Moore Melissa J.

Funder

National Institutes of Health

Publisher

Elsevier BV

Reference66 articles.

1. Optimization of non-coding regions for a non-modified mRNA COVID-19 vaccine;Gebre;Nature,2022

2. Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics;Leppek;Nat. Commun.,2022

3. Human 5′ UTR design and variant effect prediction from a massively parallel translation assay;Sample;Nat. Biotechnol.,2019

4. mRNA structure regulates protein expression through changes in functional half-life;Mauger;Proc. Natl. Acad. Sci. USA,2019

5. Algorithm for optimized mRNA design improves stability and immunogenicity;Zhang;Nature,2023

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The rational design of mRNA vaccine: From empirical method to artificial intelligence-based design;Chinese Science Bulletin;2024-09-01

2. Calibrated ribosome profiling assesses the dynamics of ribosomal flux on transcripts;Nature Communications;2024-08-26

3. Translation efficiency covariation across cell types is a conserved organizing principle of mammalian transcriptomes;2024-08-11

4. Engineering of mRNA vaccine platform with reduced lipids and enhanced efficacy;2024-08-08

5. Respiratory Syncytial Virus (RSV) optimizes the translational landscape during infection;2024-08-03