Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

Author:

Garg Garima,Muschaweckh Andreas,Moreno Helena,Vasanthakumar Ajithkumar,Floess Stefan,Lepennetier Gildas,Oellinger Rupert,Zhan Yifan,Regen Tommy,Hiltensperger Michael,Peter Christian,Aly Lilian,Knier Benjamin,Palam Lakshmi Reddy,Kapur Reuben,Kaplan Mark H.,Waisman Ari,Rad Roland,Schotta Gunnar,Huehn Jochen,Kallies Axel,Korn Thomas

Funder

Deutsche Forschungsgemeinschaft

German Ministry of Education and Research

Helmholtz Gemeinschaft

ERC

National Health and Medical Research Council

Sylvia and Charles Viertel foundation

National Multiple Sclerosis Society

Victorian State Government Operational Infrastructure Support

Australian Government NHMRC Independent Research Institute Infrastructure Support

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference77 articles.

1. Regulatory T cells: recommendations to simplify the nomenclature;Abbas;Nat. Immunol.,2013

2. Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory;Agarwal;J. Immunol.,2009

3. Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response;Bailey-Bucktrout;Immunity,2013

4. Differential regulation of effector and fegulatory T cell function by Blimp1;Bankoti;Sci. Rep.,2017

5. IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10- and IL-4-deficient and transgenic mice;Bettelli;J. Immunol.,1998

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