An efficient synthesis of (7S,10R)-2-bromo-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole: application in the preparation and structural confirmation of a potent 5-HT6 antagonist-Reference-Cited by-同舟云学术

An efficient synthesis of (7S,10R)-2-bromo-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole: application in the preparation and structural confirmation of a potent 5-HT6 antagonist

Published:2012-12 Issue:22-23 Volume:23 Page:1522-1527
ISSN:0957-4166
Container-title:Tetrahedron: Asymmetry
language:en
Short-container-title:Tetrahedron: Asymmetry

Author:

Isherwood Matthew L.,Guzzo Peter R.,Henderson Alan J.,Hsia Ming Min,Kaur Jagjit,Nacro Kassoum,Narreddula Venkateswara R.,Panduga Shailaja,Pathak Rashmi,Shimpukade Bharat,Tan Valentina,Xiang Kai,Qiang Zhu,Ghosh Animesh

Publisher

Elsevier BV

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Catalysis

Reference15 articles.

1. The 5-hydroxytryptamine 6 receptor: localisation and function

2. A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory

3. 5-HT6 Receptor Antagonists as Potential Therapeutics for Cognitive Impairment

4. Double-Blind, Controlled Phase II Study of a 5-HT6 Receptor Antagonist, SB-742457, in Alzheimers Disease

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