Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms-Reference-Cited by-同舟云学术

Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms

Published:1992-01 Issue:2 Volume:43 Page:225-235
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

fuhr Uwe,Doehmer Johannes,Battula Narayana,Wölfel Catherine,Kudla Christine,Keita Yango,Staib A.Horst

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. Human cytochrome P450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines;Butler,1989

2. Activation of promutagens by human cDNA-expressed cytochrome P450s;Gonzalez;Mutat Environ,1990

3. 4-Quinolones inhibit biotransformation of caffeine;Harder;Eur J Clin Pharmacol,1988

4. Verapamil-induced inhibition of theophylline in healthy humans;Nielsen-Kudsk;Pharmacol Toxicol,1990

5. Biotransformation of caffeine by microsomes;Kalow,1988

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