Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine

Author:

Navé Jean-Francois,Eschbach Anne,Wolff-Kugel Dominique,Halazy Serge,Balzarini Jan

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference32 articles.

1. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3-dideoxynucleosides;Mitsuya,1986

2. Initial studies on the cellular pharmacology of 2',3'-dideoxyinosine, an inhibitor of HIV infectivity;Ahluwalia;Biochem Pharmacol,1987

3. Metabolic pathways for the activation of the antiretroviral agent 2',3'-dideoxyadenosine in human lymphoid cells;Johnson;J Biol Chem,1988

4. Phosphorylation of 2',3'-dideoxyinosine by cytosolic 5'-nucleotidase of human lymphoid cells;Johnson;Mol Pharmacol,1989

5. A comparison of 2',3'-dideoxynucleoside-5'-triphosphates as inhibitors of retroviral reverse transcriptases;Hao,1987

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