Metabolism of N-acetyl-l-cysteine Some structural requirements for the deacetylation and consequences for the oral bioavailability

Author:

Sjödin Karin,Nilsson Elisibeth,Hallberg Anders,Tunek Anders

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference29 articles.

1. Intravenous N-acetylcysteine: the treatment of choice for paracetamol poisoning;Prescott;Br Med J,1979

2. Oral acetylcysteine reduces exacerbation rates in chronic bronchitis: report of a trial organized by the Swedish Society for Pulmonary Diseases;Boman;Eur J Resp Dis,1983

3. Mechanism of action of N-acetylcysteine in the protection against the hepatotoxicity of acetaminophen in rats in vivo;Lauterburg;J Clin Invest,1983

4. Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-l-cysteinein vivo: studies with N-acetyl-d-cysteine in mice;Corcoran;J Pharmacol Exp Ther,1986

5. Pharmacokinetics of N-acetylcysteine in man;Borgström;Eur J Clin Pharmacol,1986

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