Direct observation of a fluorinated anticonvulsant in brain tissue using 19F-NMR techniques

Author:

Canney Daniel J.,Covey Douglas F.,Evers Alex S.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference30 articles.

1. Anticonvulsant properties of α-, γ-, and α,γ-substituted γ-butyrolactones;Klunk;Mot Pharmacol,1982

2. Alkylsubstituted thiolo-, thiono-, and dithio-γ-butryolactones: New classes of convulsant and anticonvulsant agents;Levine;J Med Chem,1986

3. [35S]t-Butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to γ-aminobutyric acid-A and ion recognition sites;Squires;Mol Pharmacol,1983

4. Convulsant and anti-convulsant gammabutyrolactones bind at the picrotoxinin/t-butylbicyclophosphorothionate (TBPS) receptor;Levine;Biochem Pharmacol,1985

5. Binding interactions of convulsant and anticonvulsant γ-butyrolactones and γ-thiobutyrolactones with the picrotoxin receptor;Holland;J Pharmacol Exp Ther,1990

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