Selectivity of isoprenoid-containing imidazole antifungal compounds for sterol 14-demethylase P450 (P45014dm) and 7-ethoxycoumarin O-deethylase P450 of rat liver microsomes

Author:

Tamami Ito,Yuri Aoyama,Koichi Ishida,Michinari Kudoh,Kimihiko Hori,Shuichi Tsuchiya,Yuzo Yoshida

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference25 articles.

1. Yeast cytochrome P-450 catalyzing lanosterol 14α-demethylation: I. Purification and spectral properties;Yoshida;J Biol Chem,1984

2. Biochemical targets for antifungal azole derivatives: hypothesis on the mode of action;Van den Bossche,1985

3. Microsomal enzymes of cholesterol biosynthesis. Purification of lanosterol 14α-methyl demethylase cytochrome P450 from hepatic microsomes;Trzaskos;J Biol Chem,1986

4. Interaction of azole antifungal agents with cytochrome P-45014dm purified from Saccharomyces cerevisiae microsomes;Yoshida;Biochem Pharmacol,1987

5. Cytochrome P-450 of fungi: primary target for azole antifungal agents;Yoshida,1988

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