Substrate stereoselectivity and enantiomer/enantiomer interaction in propranolol metabolism in rat liver microsomes

Author:

Masubuchi Yasuhiro,Yamamoto Luis Aquira,Uesaka Mineko,Fujita Shoichi,Narimatsu Shizuo,Suzuki Tokuji

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference29 articles.

1. Uptake of propranolol by isolated guinea-pig atria;Potter;J Pharmacol Exp Ther,1967

2. The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias;Barrett;Br J Pharmacol,1968

3. Stereochemistry of the in vivo disposition and metabolism of propranolol in dog and man using deuterium-labeled pseudoracemates;Walle;Drug Metab Dispos,1985

4. Stereoselective delivery and actions of beta receptor antagonists;Walle;Biochem Pharmacol,1988

5. Racemic (R, S)-propranolol versus half-dosed optically pure (S)-propranolol in humans at steady-state: hemodynamic effects, plasma concentrations, and influence on thyroid hormone levels;Stoschitzky;Clin Pharmacol Ther,1992

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