Alterations of surface morphology caused by the metabolism of menadione in mammalian cells are associated with the oxidation of critical sulfhydryl groups in cytoskeletal proteins

Author:

Mirabelli F.,Salis A.,Perotti M.,Taddei F.,Bellomo G.,Orrenius S.

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference27 articles.

1. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated rat hepatocytes;Thor;J Biol Chem,1982

2. Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes;DiMonte;Arch Biochem Biophys,1984

3. Menadione-induced cytotoxicity is associated with protein thiol oxidation and alterations in intracellular Ca2+ homeostasis;DiMonte;Arch Biochem Biophys,1984

4. Formation and reduction of glutathione-protein mixed disulfides during oxidative stress;Bellomo;Biochem Pharmacol,1987

5. The metabolism of menadione impairs the ability of rat liver mitochondria to take up and retain Ca2+;Bellomo;J Biol Chem,1982

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