In silico and in vivo analysis reveal impact of c-Myc tag in FMC63 scFv-CD19 protein interface and CAR-T cell efficacy-Reference-Cited by-同舟云学术

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In silico and in vivo analysis reveal impact of c-Myc tag in FMC63 scFv-CD19 protein interface and CAR-T cell efficacy

Published:2024-12 Issue: Volume:23 Page:2375-2387
ISSN:2001-0370
Container-title:Computational and Structural Biotechnology Journal
language:en
Short-container-title:Computational and Structural Biotechnology Journal

Author:

Lima Ana Julia Ferreira,Hajdu Karina Lobo,Abdo Luiza,Batista-Silva Leonardo Ribeiro,de Oliveira Andrade Clara,Correia Eduardo Mannarino,Aragão Emmanuel Arthur Albuquerque,Bonamino Martín Hernán,Lourenzoni Marcos Roberto

Funder

Carlos Chagas Filho Foundation for Research Support of Rio de Janeiro State

Coordination of Higher Education Personnel Improvement

National Institute for Cancer

National Council for Scientific and Technological Development

Publisher

Elsevier BV

Reference65 articles.

1. Killing mechanisms of chimeric antigen receptor (CAR) T cells;Benmebarek;Int J Mol Sci,2019

2. Recent advances and discoveries in the mechanisms and functions of CAR T cells;Larson;Nat Rev Cancer,2021

3. Limitations in the design of chimeric antigen receptors for cancer therapy;Stoiber;Cells,2019

4. Chimeric antigen receptor signaling: functional consequences and design implications;Lindner;Sci Adv,2020

5. Structural determinants of chimeric antigen receptor design;Abdo;Crit Rev Immunol,2021

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